BioCentury | Oct 9, 2014
Distillery Therapeutics

Indication: Cancer

...Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer MicroRNA-33a (miR-33a); phosphodiesterase-8A (PDE-8A); UV radiation resistance associated (UVRAG)...
...In patient glioblastoma multiforme samples, high expression of miR-33a and low expression of PDE-8A and UVRAG...
...a miR-33a-targeting locked nucleic acid (LNA) led to decreased tumor growth and increased PDE-8A and UVRAG...
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