BioCentury | Oct 6, 2016
Distillery Therapeutics

Therapeutics: TRAF2 and NCK interacting kinase (TNIK)

...inhibiting TNIK could help treat colorectal cancer. In a human colorectal carcinoma cell line, the TNIK...
...the safety of NCB-0846. Carna Biosciences Inc. has NCB-0846 in preclinical testing for cancer. TARGET/MARKER/PATHWAY: TRAF2 and NCK interacting kinase (TNIK)...
BioCentury | Oct 29, 2009
Distillery Therapeutics

Indication: Cancer

...Licensing status Publication and contact information Cancer Colon cancer TRAF2 and NCK interacting kinase (TNIK) In vitro studies suggest that TNIK...
...could help treat colon cancer. In mouse small intestinal crypts and colon cancer cell lines, TNIK...
...suggesting TNIK activates Wnt signaling in colon cancer. Next steps could include developing small molecule TNIK...
BioCentury | Oct 29, 2009
Targets & Mechanisms

Wnt it rains

...researchers have added a downstream target- TRAF2 and NCK interacting kinase (TNIK)-to the mix. Using proteomics, the group showed that TNIK...
...noted Mahmoudi. "A next step could be designing a specific small molecule inhibitor for TNIK." TNIK...
...there as well as with TNIK, he told SciBX . Moon wanted to know whether TNIK's...
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