BioCentury | Aug 1, 2020
Product Development

Will Biocon’s COVID-19 anti-inflammatory succeed where IL-6 blockers have failed? developing Alzumab for COVID-19 at about $3.5 billion. Targets IL-6 - Interleukin-6 TNF alpha - Tumor necrosis factor (TNF) alpha Stephen...
BioCentury | Jul 17, 2020
Product Development

Vaccine developments in China include IND acceptance for Fosun, Phase II start for Chongqing Zhifei

...N) Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 (NF-kB) (NFKB1) (p105) (p50) Tumor necrosis factor (TNF) alpha Interleukin-6...
BioCentury | Jun 27, 2020
Product Development

BARDA no longer funding immunomodulators as support for the therapeutic class to treat COVID-19 grows

...p38 MAPK (MAPK14) - p38 mitogen-activated protein kinase SGLT2 - Sodium-glucose cotransporter 2 TNFα - Tumor necrosis factor alpha Elizabeth...
BioCentury | Jun 2, 2020

Hillhouse-backed $160M series B round to drive Genor’s first candidate to the market

...Co. Ltd. CD20 Epidermal growth factor receptor 2 (HER2) (EGFR2) (ErbB2) (neu) Programmed cell death 1 (PD-1) (PDCD1) (CD279) Tumor necrosis factor (TNF) alpha...
BioCentury | Apr 15, 2020
Product Development

AZ targeting cytokine storms as ranks of repurposed agents for COVID-19 grow

...kinase IL-6 - Interleukin-6 IL-10 - Interleukin-10 MCP-1 (CCL2) - Monocyte chemoattractant protein-1 TNFα - Tumor necrosis factor alpha Elizabeth...
BioCentury | Mar 28, 2020
Product Development

COVID-19 roundup: FDA approves Abbott’s 5-minute test; plus Trump signs stimulus bill, WHO readies master protocol, CytoDyn mAb data and more

... . Targets CCR5 (CD195) - CC chemokine receptor 5 IL-6 - Interleukin-6 TNFα - Tumor necrosis factor alpha Elizabeth...
BioCentury | Jan 18, 2020
Product Development

Charting a course to intercepting Type I diabetes

...see “IBM, JDRF Pinpointing T1D Risk Factors” ). Targets IL-10 - Interleukin 10 TNFα - Tumor necrosis factor alpha Allison...
BioCentury | Jan 10, 2020
Product Development

Seeking structural endpoints for OA

...kinase 1A MDM2 (HDM2) - Mdm2 p53 binding protein homolog TP53 - p53 TNF - Tumor necrosis factor alpha Stephen...
BioCentury | Dec 10, 2019
Company News

Janssen pays $750M for XBiotech's dermatology candidate after positive Phase II data

...IL-1α - Interleukin-1 alpha; IL-3 - Interleukin-3; IL-4R (IL-4RA; CD124) - Interleukin-4 receptor; TNFα - Tumor necrosis factor alpha Elizabeth...
BioCentury | Nov 26, 2019
Company News

Nov. 26 Company Quick Takes: Kyowa, Ardelyx expand partnership; plus ICER, Celltrion, Asahi-Veloxis and Merck

...Targets: JAK-1 - Janus kinase-1; PD-1 (PDCD1; CD279) - Programmed cell death 1; TNFα - Tumor necrosis factor alpha Elizabeth...
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