BioCentury | Oct 22, 2015
Strategy

Singles club

...National Institute of Biomedical Imaging and Bioengineering. He oversees the Single Cell Analysis Program ( SCAP...
...San Diego and the University of Southern California . Together with Fluidigm's single-cell institutes, the SCAP...
...the data. He said that is a key focus of the three centers funded by SCAP...
BioCentury | Jan 22, 2015
Finance

Public Funding Notebook: Small change for NIH

...Bethesda, Md. Tables Public funding highlights 12/30 NIH NIH Common Fund's Single Cell Analysis Program (SCAP...
BioCentury | Dec 17, 2009
Targets & Mechanisms

Deprogramming stroke

...[ b ]. After INSIG1 is degraded [ c ], SREBP1 and its carrier protein, SREBF chaperone (SCAP)...
...INSIG1 degradation. Kamisuki et al. have shown that a small molecule, fatostatin, that binds to SCAP...
...induced gene 1 (INSIG1) that confines both SCAP and SREBP1 to the ER. "INSIG1 and SCAP...
BioCentury | Sep 3, 2009
Distillery Therapeutics

Indication: Metabolic disease

...and contact information Metabolic disease Metabolic disease Sterol regulatory element binding protein (SREBP); SREBP chaperone (SCAP...
BioCentury | Dec 3, 2001
Tools & Techniques

Static around statins

...as SCAP, through SCAP's sterol binding element. Normally, when cells are deficient in cholesterol, the SREBP-SCAP...
...SCAP-SREBP complex, and increasing transcription of the LDLr gene. But they also showed that the SCAP...
...the SCAP-SREBP pathway normally is then modified to decrease LDLr expression. Concomitant use of the SCAP...
BioCentury | Dec 3, 2001
Company News

GlaxoSmithKline other research news

...the identification of a class of compounds that bind to the sterol responsive element of SCAP...
...GlaxoSmithKline plc (GSK; LSE:GSK), London, U,K. Product: GW532 small molecule SREBP cleavage activating protein ( SCAP...
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