BioCentury | Mar 29, 2012
Distillery Therapeutics

Indication: Endocrine/metabolic disease

...and contact information Endocrine/metabolic disease Diabetes Sphingosine-1-phosophate phosphatase 1 (SGPP1) Cell culture studies suggest antagonizing SGPP1...
...decreased glucose-induced insulin secretion compared with no blockade. In these cells, small interfering RNA against SGPP1...
...sphingosine-1-phosphate, increased sphingosine-1-phosphate and insulin levels compared with nontargeted control siRNA. Next steps include identifying SGPP1...
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