...and contact information Endocrine/metabolic disease Diabetes Solute carrier family 30 zinc transporter member 8 (SLC30A8; ZNT8) Human genetic studies suggest inhibiting SLC30A8... ...or treat type 2 diabetes. Previous studies in mice had alternatively suggested that loss of SLC30A8... ...2 diabetes. Genotyping and analysis of about 150,000 individuals showed that carriers of mutations in SLC30A8...
...studies are needed to flesh out the functional consequences of expression of ZNT8 (solute carrier family 30 zinc transporter member 8; SLC30A8... ...multiple population cohorts identified 12 different ZNT8 variants that encoded a truncated version of the ZNT8... ...how the phenotype compares with that of human carriers of the protective ZNT8 variants. Homozygous Znt8...
...information Endocrine/metabolic disease Diabetes Solute carrier family 30 zinc transporter member 8 (SLC30A8; ZNT8) Mouse and human studies suggest stimulating pancreatic SLC30A8... ...Mouse and human studies suggest stimulating pancreatic SLC30A8 could help treat diabetes. Humans with the SLC30A8... ...have an elevated risk of developing type 2 diabetes. In mice, b cell-specific knockout of Slc30a8...
Following last week's downturn in the Neuer Markt, oncology and endocrinology play Zentaris (Proposed-NMarkt:ZNT) postponed its IPO. The company, which is being spun out of Asta Medica, was offering 6 million shares at EUR11-EUR14 and...
Cor Therapeutics' decision to pad its coffers with $250 million via convertible notes had the M&A rumor mill abuzz last week. Scuttlebutt largely centered on the company's prospects for putting a second product into the...