13:53 , Oct 31, 2017 |  BC Innovations  |  Distillery Therapeutics

Cardiovascular

INDICATION: Myocardial infarction (MI) Mouse studies suggest inhibiting SAV1 could help treat MI. In a mouse model of MI, cardiomyocyte-specific knockout of SAV1 decreased fibrosis in the left ventricle, increased the number of cardiomyocytes in...
08:00 , Jan 28, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Liver cancer Serine/threonine kinase 4 (STK4; MST1); Serine/threonine kinase 3 (STK3) (MST2); SAV1 salvador family WW domain containing protein 1 (SAV1) Studies in mice suggest...