08:00 , Nov 5, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: S100 calcium binding protein A7 (S100A7; psoriasin)

Infectious disease INDICATION: Fungal infection Rodent studies identified a reduced form of S100A7 that could help treat fungal infections. Analysis of skin samples from psoriasis patients - whose lesions are resistant to fungal infections -...
07:00 , May 29, 2014 |  BC Innovations  |  Targets & Mechanisms

S100A9-clot not, bleed not

Although the new generation of antithrombotic drugs provides marked improvements over warfarin, they all still carry bleeding risk. S100 calcium binding protein A9 could represent a new target that, when blocked, prevents thrombosis without increasing...
08:00 , Jan 13, 2011 |  BC Innovations  |  Distillery Techniques

Technology: Disease models

This week in techniques Approach Summary Licensing status Publication and contact information Disease models Mouse model of psoriasis susceptibility Transgenic mice expressing human psoriasin (S100 calcium binding protein A7; S100A7) and S100A7A (S100A15) in skin...