BC Extra | Jun 26, 2019
Clinical News

June 25 Clinical Quick Takes: Minerva meets in insomnia; plus Aldeyra, Genkyotex and more

Minerva rises with insomnia data  Seltorexant (MIN-202) from Minerva Neurosciences Inc. (NASDAQ:NERV) met the primary endpoint of reducing Latency to Persistent Sleep (LPS) at night 1 vs. placebo (p≤0.001) in a Phase IIb trial to...
BC Extra | Mar 26, 2019
Clinical News

Aldeyra's allergic conjunctivitis therapy clears Phase III hurdle

Aldeyra shares rose $2.57 (36%) to $9.71 on Tuesday after the company said both doses of reproxalap (ADX-102) met the primary endpoint in the Phase III ALLEVIATE trial to treat allergic conjunctivitis. The small molecule...
BC Extra | Sep 28, 2018
Financial News

Aldeyra, Nightstar price follow-ons

Aldeyra Therapeutics Inc. (NASDAQ:ALDX) and Nightstar Therapeutics plc (NASDAQ:NITE) each priced follow-ons Thursday, raising a total of about $144 million. Aldeyra raised $72.2 million through the sale of 5.3 million shares at $13.75 in a...
BC Week In Review | Sep 28, 2018
Clinical News

Aldeyra planning Phase III program for dry eye disease therapy

Aldeyra Therapeutics Inc. (NASDAQ:ALDX) reported that reproxalap (ADX-102) significantly reduced ocular dryness and discomfort in a Phase IIb trial to treat dry eye disease. The company plans to start Phase III testing of the candidate...
BC Extra | Sep 26, 2018
Clinical News

Aldeyra planning Phase III program for dry eye disease therapy

Aldeyra Therapeutics Inc. (NASDAQ:ALDX) added $3.45 (35%) to $13.35 on Wednesday after reporting that reproxalap (ADX-102) significantly reduced ocular dryness and discomfort in a Phase IIb trial to treat dry eye disease. The company plans...
BC Innovations | Jan 6, 2017
Product R&D

Viral ambitions

  Meissa Vaccines Inc. is translating studies from an Emory University team into a pair of vaccine platforms to protect specific at-risk subpopulations from infections by two otherwise innocuous viruses, RSV and the common cold....
BC Innovations | Jan 3, 2017
Distillery Therapeutics

Infectious disease

INDICATION: Respiratory syncytial virus (RSV) Rat studies suggest a live attenuated RSV vaccine engineered to stably express the prefusion conformation of RSV F protein could help prevent RSV infection. The vaccine expressed an RSV F...
BC Week In Review | Aug 15, 2016
Clinical News

Topical NS2: Phase II data

A double-blind, U.S. Phase II trial in 12 Sjogren-Larsson syndrome patients with moderate to severe ichthyosis showed that once-daily 1% topical NS2 administered on a 4x10 inch area of skin for 2 months significantly improved...
BC Week In Review | Mar 7, 2016
Clinical News

NS2: Phase IIa data

Top-line data from a double-blind, Canadian Phase IIa trial in 100 patients with induced seasonal allergic conjunctivitis showed that 0.5% NS2 ophthalmic drops significantly reduced ocular itching and tearing vs. vehicle ophthalmic drops (p<0.05 for...
BC Week In Review | Nov 9, 2015
Clinical News

NS2: Phase IIa started

Aldeyra began a double-blind, placebo-controlled, Canadian Phase IIa trial to evaluate 0.5% NS2 ophthalmic drops in about 100 patients. Aldeyra Therapeutics Inc. (NASDAQ:ALDX), Burlington, Mass.   Product: NS2   Business: Inflammation   Molecular target: NA...
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