BioCentury | Apr 4, 2020
Product Development

COVID-19 roundup: FDA’s expanded access program for convalescent plasma; plus more funding from BARDA, tests from Eurofins, BD-BioGx, and more

BARDA’s latest push into plasma-based COVID-19 therapies includes an expanded access program for convalescent plasma and funding for Emergent’s hyperimmune program. To combat the pandemic, a pair of companies began rolling out tests, while GSK...
BioCentury | Apr 4, 2020
Management Tracks

CureVac names Stéphenne chairman; plus Desmond-Hellmann to Pfizer’s board, Reagan-Udall, Kyowa Hakko, Assembly, BioCryst and more

CureVac AG said Deputy Chairman Jean Stéphenne will become chairman. He is the former president and chairman of the biologicals unit of GlaxoSmithKline plc (LSE:GSK; NYSE:GSK). It's another management change for the biotech as it...
BioCentury | Apr 3, 2020
Product Development

April 2 Quick Takes: Horizon takes out Curzion; plus Rgenta, Merck, Novartis-Aurobindo, Kite, Teneobio and Seattle Genetics

Horizon gains sclerosis candidate via Curzion deal  Horizon Therapeutics plc (NASDAQ:HZNP) acquired privately held Curzion Pharmaceuticals Inc., giving it LPAR1 antagonist HZN-825 (CZN001). Curzion’s shareholders received $45 million up front and are eligible for milestones...
BioCentury | Apr 3, 2020
Product Development

COVID-19: manufacturing mAbs in patients

The urgency and scale of the coronavirus outbreak could drive progress in an emerging therapeutic strategy suited to rapid development and distribution -- encoding of antibodies in RNA or DNA. Neutralizing mAbs against SARS-CoV-2 have...
BioCentury | Apr 1, 2020
Distillery Therapeutics

Base editor correction of TERT promoter mutations for glioma

DISEASE CATEGORY: Cancer INDICATION: Brain cancer Gene editing with a CRISPR base editor to correct mutations in the TERT promoter could treat gliomas harboring those mutations. An adeno-associated virus serotype 2 (AAV2) vector delivering an...
BioCentury | Apr 1, 2020
Product Development

A primer on the new coronavirus and COVID-19: BioCentury editors in conversation

The rapid pace at which COVID-19 has transformed society has rippled through the biopharma industry, affecting not only companies’ business strategies, but their product pipelines and priorities as many of them adapt on the fly...
BioCentury | Mar 28, 2020
Product Development

COVID-19 crisis spurs innovation in rapid diagnostic technologies

Companies across the world are mobilizing to answer the call for diagnostic innovation brought on by the COVID-19 crisis. The advances made during this time could change the course of this and future outbreaks, but...
BioCentury | Mar 28, 2020
Product Development

COVID-19 diagnostic tech tableau

In the ramp-up of testing for COVID-19, two well-established technologies have divided the forefront: RT-PCR and immunoassays. The former tests for active infection by detecting viral RNA, while the latter can be used to detect...
BioCentury | Mar 28, 2020
Management Tracks

Bernard joins Qiagen as CEO; plus CytomX, Recursion, 89bio, Heptares, Fusion, Freeline, Cognition, I-Mab, Seres and more

Qiagen N.V. (NYSE:QGEN; Xetra:QIA) said Thierry Bernard will become the permanent CEO after serving on an interim basis since October. Bernard, who joined Qiagen in 2015 as SVP of the molecular diagnostics business area, takes...
BioCentury | Mar 26, 2020
Emerging Company Profile

ReCode: merging RNA therapies and organ-specific delivery for respiratory diseases

ReCode Therapeutics launched on Thursday with an OrbiMed- and Colt Ventures-led $80 million series A round to pair RNA therapeutics for rare respiratory diseases with an organ-specific lipid nanoparticle delivery technology. The company was formed...
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