BioCentury | Oct 13, 2016
Distillery Therapeutics

Therapeutics: Ring finger protein 20 (RNF20); RNF40; kinesin spindle protein (KSP; Eg5; KIF11)

...Cancer INDICATION: Breast cancer Cell culture and mouse studies suggest inhibiting RNF20 , RNF40 or KSP...
...KSP could help treat breast cancer. In a human breast adenocarcinoma cell line, siRNA targeting RNF20...
...apoptosis compared with vehicle. In a xenograft mouse model of breast cancer, tumor knockdown of RNF20...
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