19:00 , Jan 4, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: December 2017

New Therapeutic Targets and Biomarkers: December 2017 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during December 2017. Therapeutic targets are defined as any protein, gene or other...
01:15 , Dec 13, 2017 |  BC Innovations  |  Distillery Therapeutics

Cardiovascular

INDICATION: Atherosclerosis Mouse studies suggest inhibiting ARHGEF1 could help treat atherosclerosis. In an LDLR-deficient mouse model of atherosclerosis, ARHGEF1 knockout decreased the formation of atherosclerotic lesions compared with normal expression. In two bone marrow-ablated, LDLR-deficient...