BioCentury | Jul 13, 2018
Preclinical News

RXR a potential minimal residual disease target in melanoma

...frequently found in biopsies from patients undergoing treatment. The model predicted that RXR gamma (RXRG; RXRgamma...
...Leuven BRAF MAP kinase kinase 1 (MAP2K1) (MEK1) MAP kinase kinase 2 (MAP2K2) (MEK2) MEK Retinoid X receptor (RXR) Retinoid X receptor gamma (RXRG) (RXRgamma...
BioCentury | Dec 19, 2013
Distillery Therapeutics

Indication: Cancer

...Colon cancer Retinoid X receptor-g (RXRG; RXRg) In vitro and mouse studies suggest spironolactone or RXRg...
...cells, but siRNAs targeting RXRg did block the effects of spironolactone. Next steps include identifying RXRg...
BioCentury | Jan 6, 2011
Targets & Mechanisms

More mileage out of myelin

...Rxr signaling were more highly expressed during the natural regeneration process. Retinoid X receptor- g( Rxrg...
...importance of RXRG expression in MS by using postmortem brain sections from MS patients. Indeed, RXRG...
...active borders of lesions but not in cells within the chronic inactive core, suggesting that RXRG...
BioCentury | Dec 16, 2010
Distillery Therapeutics

Indication: Autoimmune disease

...Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) Retinoid X receptor-g (RXRG; RXRg...
BioCentury | Feb 9, 1998
Company News

INSERM other research news

...reductions in standard movement tests of dopamine-mediated motor skills. The receptors, RARbeta, RXRbeta , and RXRgamma...
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