BioCentury | Jun 4, 2019
Distillery Therapeutics

RELMα and RETN for Gram-positive and Gram-negative bacterial infections

...S. pyogenes , P. aeruginosa , P. acnes and other bacterial infections. TARGET/MARKER/PATHWAY: Resistin (RETN); resistin...
...Lora V. Hooper, same affiliation as above email: lora.hooper@utsouthwestern.edu Mark Zipkin University of Texas Southwestern Medical Center Resistin (RETN) Resistin...
BioCentury | Jan 4, 2018
Translation in Brief

New Therapeutic Targets and Biomarkers: December 2017

...Technology and Research (A*STAR); Novartis AG (NYSE:NVS; SIX:NOVN); Beijing Institute of Microbiology and Epidemiology Sepsis Resistin...
BioCentury | Dec 19, 2017
Distillery Therapeutics

Infectious disease

...RETN-derived peptide in a mouse model of sepsis and in blood from septic patients. TARGET/MARKER/PATHWAY: Resistin...
...CONTACT: Meera G. Nair, University of California, Riverside, Calif. email: meera.nair@ucr.edu Karen Tkach Tuzman University of California Riverside Resistin...
BioCentury | Dec 5, 2011
Product Development

Change-up for BATTER-UP

...MMP1) and MMP3 , chitinase 3-like 1 cartilage glycoprotein-39 ( CHI3L1 ; YKL40 ), leptin, resistin...
BioCentury | Aug 6, 2009
Targets & Mechanisms

Signaling insulin resistance in obesity

...their function in the human condition remains unclear. As a case in point, Lavan cited resistin...
BioCentury | Apr 30, 2009
Distillery Therapeutics

Indication: Inflammation

...week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Inflammation Inflammation Resistin-like-α...
...production than that seen in wild-type controls. Next steps include determining how the Retnla-related human resistin...
BioCentury | Feb 19, 2009
Targets & Mechanisms

Resistin becomes less futile

...isn't clear if it will rekindle enthusiasm for resistin itself as a drug target. When resistin...
...mouse model expresses resistin only in macrophages. 2 "The wrinkle came shortly after we discovered resistin...
...resistin are associated with metabolic syndrome and diabetes. 3,4 But the questions of how-and if-macrophage-produced resistin...
BioCentury | Feb 12, 2009
Distillery Techniques

Technology: Disease models

...information Disease models Mouse model of human resistin expression A mouse model expressing macrophage-derived human resistin...
...the development of compounds to prevent insulin resistance and treat type 2 diabetes. In humans, resistin...
...did not express any resistin. Next steps include using the model to screen for potential resistin...
BioCentury | Jan 22, 2001
Company News

University of Pennsylvania other research news

...explain the link between Type II diabetes and obesity. They reported that the peptide hormone resistin...
...resistin. The researchers also published in The Proceedings of the National Academy of Sciences that resistin-like...
...and in the gastrointestinal tract, especially the colon. University of Pennsylvania , Philadelphia, Penn. Product: Resistin...
BioCentury | Jan 22, 2001
Tools & Techniques

A new target for diabetes

...diabetes are strongly associated, but the biochemical basis had not been identified. A protein called resistin...
...fat cells may be that link. New work by University of Pennsylvania researchers shows that resistin...
...obesity, including leptin, tumor necrosis factor alpha (TNF-a), and free fatty acids as well as resistin...
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