08:00 , Jan 22, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Filamin A (FLNA); regulator of calcineurin 1 (RCAN1; DSC1)

Neurology INDICATION: Neurology Rat studies suggest FLNA could help treat periventricular heterotopia (PH) caused by a deficiency in RCAN1 . In rats, shRNA knockdown of RCAN1 in the brain decreased FLNA levels and neuronal migration...
08:00 , Nov 14, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Anxiety Regulator of calcineurin 1 (RCAN1; DSC1) Mouse studies suggest RCAN1 inhibition could help treat pathological and drug-induced anxiety. In mice, Rcan1 knockout increased calcineurin...
07:00 , Aug 6, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Various

Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Inflammatory diseases; sepsis Regulator of calcineurin 1 (RCAN1; DSCR1) Studies in mice suggest that increasing DSCR1 expression could be useful for treating inflammatory diseases or...