BioCentury | Aug 16, 2017
Distillery Techniques

Biomarkers

TECHNOLOGY: Tissue markers Tumor levels of a panel of mRNA splice variants could help diagnose prostate cancer in African-Americans and levels of one PI3KCD variant could help predict survival. Transcriptomic analysis of tumor samples from...
BioCentury | May 23, 2017
Distillery Therapeutics

Cancer

...inhibiting PRKCD , PKCE or RASGRP3 could help treat GNAQ -mutant uveal melanoma. Levels of RASGRP3...
...three normal human melanocyte cell lines. In three of the GNAQ-mutant cell lines, knockdown of RASGRP3...
...In two of the GNAQ-mutant cell lines, knockdown of both PRKCD and PKCE, which regulate RASGRP3...
BioCentury | Sep 17, 2009
Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) Mitogen-activated protein kinase kinase (MEK); p38 mitogen-activated protein kinase (p38 MAPK; MAPK14); calcium and DAG-regulated guanine nucleotide exchange factor 1...
BioCentury | Feb 5, 2009
Distillery Therapeutics

Indication: Neurology

This week in therapeutics Indication Target/ marker/ pathway Summary Licensing status Publication and contact information Neurology Parkinson's disease (PD) Calcium and DAG-regulated guanine nucleotide exchange factor 1 (RASGRP1; CALDAG-GEFI); Calcium and DAG-regulated guanine nucleotide exchange...
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