BioCentury | Aug 16, 2017
Distillery Techniques

Biomarkers

...in European-American patients, including the oncogenes PIK3CD, fibroblast growth factor receptor 3 (FGFR3; CD333) and RAS guanyl releasing protein 2 (RASGRP2)...
...University Fibroblast growth factor (FGF) receptor 3 (FGFR3) (CD333) Phosphoinositide 3-kinase (PI3K) catalytic subunit delta polypeptide (PI3KCD) (P110delta) RAS guanyl releasing protein 2 (RASGRP2)...
BioCentury | May 23, 2017
Distillery Therapeutics

Cancer

INDICATION: Melanoma Cell culture studies suggest inhibiting PRKCD , PKCE or RASGRP3 could help treat GNAQ -mutant uveal melanoma. Levels of RASGRP3 were higher in five human GNAQ-mutant uveal melanoma cell lines than in four human...
BioCentury | Sep 17, 2009
Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) Mitogen-activated protein kinase kinase (MEK); p38 mitogen-activated protein kinase (p38 MAPK; MAPK14); calcium and DAG-regulated guanine nucleotide exchange factor 1...
BioCentury | Feb 5, 2009
Distillery Therapeutics

Indication: Neurology

...Neurology Parkinson's disease (PD) Calcium and DAG-regulated guanine nucleotide exchange factor 1 (RASGRP1; CALDAG-GEFI); Calcium and DAG-regulated guanine nucleotide exchange factor 2 (RASGRP2...
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