BioCentury | Aug 20, 2009
Targets & Mechanisms

New mechanism for sulfonylureas

...team showed that the generic sulfonylureas tolbutamide and glibenclamide agonized Epac2, which in turn activated RAP1 GTPase activating protein...
BioCentury | Aug 6, 2009
Distillery Therapeutics

Indication: Endocrine disease

...Publication and contact information Endocrine disease Diabetes Rap guanine nucleotide exchange factor 4 (RAPGEF4; EPAC2); RAP1 GTPase activating protein...
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