BioCentury | Jun 29, 2017
Translation in Brief

New Therapeutic Targets and Biomarkers: June 2017

...Euronext:TNG) Pipeline Information Infectious disease Bacterial infection PYD pyrin domain containing 2 (PYDC2) Mouse studies suggest promoting the expression of PYDC2...
BioCentury | Jun 20, 2017
Distillery Therapeutics

Infectious disease

...INDICATION: Bacterial infection Mouse studies suggest promoting the expression of PYDC2 could help treat bacterial infections...
...models of Francisella novicida , F. tularensis and Streptococcus pneumoniae infection, transgenic overexpression of human PYDC2...
...steps could include identifying and testing compounds that promote PYDC2 expression in the models. TARGET/MARKER/PATHWAY: PYD pyrin domain containing 2 (PYDC2)...
BioCentury | Sep 24, 2015
Distillery Therapeutics

Therapeutics: PYD pyrin domain containing 1 (PYDC1; ASC2)

Inflammation INDICATION: CIAS1-associated periodic syndrome (CAPS); sepsis; inflammation Mouse and patient sample studies suggest activating PYDC1 could help treat CAPS, sepsis and other inflammatory diseases. Patients with CAPS or sepsis had lower levels of PYDC1...
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