23:03 , Jun 29, 2017 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: June 2017

New Therapeutic Targets and Biomarkers: June 2017 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during June 2017. Therapeutic targets are defined as any protein, gene or other...
17:08 , Jun 21, 2017 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Pseudomonas Cell culture studies suggest inhibiting P. aeruginosa exoS could help treat infections by the pathogen. Mechanistic studies in human neutrophils co-cultured with P. aeruginosa showed that exoS induced ADP-ribosylation of host Ras that...
07:00 , Mar 27, 2014 |  BC Innovations  |  Distillery Techniques

Technology: Chemistry

Approach Summary Licensing status Publication and contact information Chemistry Hydrophobic cross-linking of peptides to create inhibitors of protein-protein interactions Hydrophobic cross-linking of peptides at critical binding residues could help generate stable, peptide-based inhibitors of protein-protein...