BioCentury | Jun 29, 2017
Translation in Brief

New Therapeutic Targets and Biomarkers: June 2017

...University School of Medicine Distillery Therapeutics Pseudomonas Pseudomonas aeruginosa exoenzyme S ( P. aeruginosa exoS) Cell culture studies suggest inhibiting P. aeruginosa exoS...
BioCentury | Jun 21, 2017
Distillery Therapeutics

Infectious disease

...INDICATION: Pseudomonas Cell culture studies suggest inhibiting P. aeruginosa exoS could help treat infections by the pathogen. Mechanistic...
...identifying compounds that inhibit exoS and testing in additional models of infection. TARGET/MARKER/PATHWAY: Pseudomonas aeruginosa exoenzyme S ( P. aeruginosa exoS...
...doi:10.1016/j.chom.2017.04.001 CONTACT: Arne Rietsch, Case Western Reserve University, Cleveland, Ohio email: arne.rietsch@case.edu Alicia Parker Case Western Reserve University Pseudomonas aeruginosa exoenzyme S...
BioCentury | Mar 27, 2014
Distillery Techniques

Technology: Chemistry

...inhibitors of protein-protein interactions involving irregular, non-alpha helical interfaces. X-ray crystallography of the interaction between Pseudomonas aeruginosa exoenzyme S...
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