BC Innovations | Jun 16, 2016
Translation in Brief

Dysfunction junction

Researchers from Memorial Sloan Kettering Cancer Center have shown brain metastases build gap junctions to flood neighboring astrocytes with pro-inflammatory signaling molecules, causing the cells to secrete cytokines that fuel tumor growth via a paracrine...
BC Innovations | Jun 2, 2016
Distillery Therapeutics

Therapeutics: Gap junction protein α 1, 43kDa (GJA1; CX43; connexin-43); protocadherin 7 (PCDH7)

Cancer INDICATION: Breast cancer; non-small cell lung cancer (NSCLC); cancer Patient sample and mouse studies suggest inhibiting GJA1 or PCDH7 could help treat brain metastases of breast cancer, NSCLC and other solid tumor types. In...
Items per page:
1 - 2 of 2