BioCentury | Nov 20, 2020
Deals

China in-licensing play LianBio follows $310M crossover round with broad Pfizer deal

...Wong contributed to this report.TARGETSFGFR – Fibroblast growth factor receptor  SHP-2 (SHPTP2; PTPN11) – Src homology protein tyrosine phosphatase...
BioCentury | Oct 29, 2020
Finance

Perceptive-backed in-licensing play LianBio to cast a wide net with $310M crossover round

...Wellington Management.TARGETSSHP-2 (SHPTP2; PTPN11) – Src homology protein tyrosine phosphatase...
BioCentury | Oct 27, 2020
Product Development

Mirati impresses with KRAS inhibitor response rates, potential biomarker

...6EGFR – Epidermal growth factor receptorKRAS (K-Ras) – KRAS proto-oncogeneSHP2 (SHPTP2; PTPN11) – Src homology protein tyrosine phosphatase...
BioCentury | Oct 2, 2020
Finance

C4 is latest preclinical protein degradation IPO with big aftermarket gain

...zinc finger 1IKZF3 (AIOLOS) - IKAROS family zinc finger 3SHP-2 (SHPTP2; PTPN11) - Src homology protein tyrosine phosphatase...
BioCentury | Sep 17, 2020
Deals

Mirati and Boehringer partner to test KRAS-KRAS combo

...a combination study with the pharma’s SHP-2 inhibitor TNO115.  TARGETSKRAS (K-Ras) SHP-2 (SHPTP2; PTPN11) – Src homology protein tyrosine phosphatase...
...Therapeutics Inc. Amgen Inc. Boehringer Ingelheim GmbH KRAS proto-oncogene, GTPase (KRAS) (K-Ras) Son of sevenless homolog 1 (SOS1) Src homology protein tyrosine phosphatase...
BioCentury | Aug 11, 2020
Emerging Company Profile

Through LianBio, Perceptive forms bridge for Western pipeline into Asia

...UndisclosedInvestors: Perceptive AdvisorsCEO: Bing LiPatents: UndisclosedTARGETSFGFR – Fibroblast growth factor receptorSHP-2 (SHPTP2; PTPN11) – Src homology protein tyrosine phosphatase...
...Wong mavacamten (SAR439152, myk-461) infigratinib (BGJ398) Perceptive Advisors BridgeBio Pharma Inc. MyoKardia Inc. Cardiac myosin Fibroblast growth factor (FGF) receptor (FGFR) Src homology protein tyrosine phosphatase...
BioCentury | Aug 5, 2020
Product Development

I-SPY COVID brings new set of targets to master protocols for acute respiratory distress

...chemokine receptor 2 CCR5 (CD195) - CC chemokine receptor 5 PDE-4 - Phosphodiesterase-4 PTPRB - Protein tyrosine phosphatase...
...BDKRB2) (B2R) CC chemokine receptor 2 (CCR2) (CD192) CC chemokine receptor 5 (CCR5) (CD195) Tyrosine kinase receptor 2 (Tie2) Protein tyrosine phosphatase...
BioCentury | Jul 16, 2020
Finance

Relay’s IPO among the year’s largest for a biotech as others wait in wings

...KGFR; CD332) - Fibroblast growth factor (FGF) receptor 2 SHP-2 (SHPTP2; PTPN11) - Src homology protein tyrosine phosphatase...
BioCentury | Jun 2, 2020
Product Development

Sanofi makes case for why its first cancer drug in a decade can take on Darzalex

...B7-H1; CD274) - Programmed cell death 1 ligand 1 SHP-2 (SHPTP2; PTPN11) - Src homology protein tyrosine phosphatase...
BioCentury | Apr 25, 2020
Targets & Mechanisms

Trends to surf for at AACR 2020

...PARP-7 - Poly(ADP-ribose) polymerase-7 PBRM1 (PB1) - Polybromo 1 SHP-2 (SHPTP2; PTPN11) - Src homology protein tyrosine phosphatase...
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