BioCentury | Mar 14, 2013
Distillery Therapeutics

Indication: Cardiovascular disease

...1 regulatory subunit 10 (PPP1R10) Patient tissue and mouse studies suggest inhibiting miR-34a or increasing PPP1R10...
...could help improve post-MI recovery. In a mouse model for MI, an miR-34a-targeting antagomir increased Ppp1r10...
...cardiac contractile function compared with a control antagomir. In the same model, vector-mediated expression of Ppp1r10...
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