07:00 , Sep 1, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Proteasome activator subunit 3 (PSME3)

Cancer INDICATION: Colorectal cancer Cell culture and mouse studies suggest combining inhibitors of PSME3 and glycosis could help treat colorectal cancer. In glucose-deprived human colon cancer cell lines, knockdown or knockout of PSME3 decreased intracellular...
07:00 , Oct 10, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Hepatic disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Hepatic disease Liver disease Proteasome activator subunit 3 (PSME3) Mouse studies suggest inhibition of the proteasome activator PSME3 could help treat and prevent liver steatosis. In...