23:28 , Jun 7, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: May 2018

New Therapeutic Targets and Biomarkers: May 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during May 2018. Therapeutic targets are defined as any protein, gene or other...
18:06 , May 15, 2018 |  BC Innovations  |  Distillery Therapeutics

Ophthalmic disease

INDICATION: Retinitis Mouse studies suggest promoting expression of the proteasome subunits PSME1 or PSMD11 could help treat retinitis pigmentosa. In a mouse model of the disease, overexpression of PSME1 or PSMD11 increased photoreceptor survival and...
21:21 , May 8, 2018 |  BC Innovations  |  Translation in Brief

Proteasome overload

Researchers at Duke University School of Medicine have found that activating proteasomes in the retina could treat degenerative retinal diseases driven by protein misfolding and expect the approach could apply to other neurodegenerative disorders. Vadim...