Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Proteasome 26S subunit ATPase 2 (PSMC2) Mouse studies suggest inhibiting PSMC2 in tumor cells could help treat cancer. In mouse xenograft models of ovarian...

Two research groups have independently shown that targeting genes carrying passenger mutations blocked growth of cancer cells and improved survival in mouse models. 1,2 Although precise therapeutic windows for such a strategy remain to be...