BioCentury | Sep 5, 2013
Distillery Therapeutics

Indication: Cancer

...Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Prostate cancer non-coding RNA 1 (PRNCR1); prostate-specific transcript 1...
...PCGEM1) In vitro, cell culture and mouse studies suggest inhibiting the long noncoding RNAs (lncRNAs) PRNCR1...
...cancer. Chromatin isolation by RNA purification and in vitro binding studies showed that the lncRNAs PRNCR1...
BioCentury | Sep 5, 2013
Targets & Mechanisms

lncRNA meets the androgen receptor

...two lncRNAs functionally contribute to prostate cancer growth. The group honed in on prostate cancer non-coding RNA 1 ( PRNCR1...
...and the RNA-binding protein pygopus homolog 2 (PYGO2). To probe the functional role of PRNCR1...
...a pathway to explain how PRNCR1 and PCGEM1 contribute to AR activity. First, AR binds PRNCR1...
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