07:00 , Jul 23, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Polymerase (DNA directed), delta 2, regulatory subunit 50kDa (POLD2); cytochrome c, somatic (CYCS); metallothionein 1A (MT1A; MTC); aldo-keto reductase family 1, member C3...
07:00 , Apr 30, 2009 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Modulation of mammalian target of rapamycin (mTOR; FRAP; RAFT1) expression to control human embryonic stem cell (hESC) differentiation and pluripotency In...
08:00 , Mar 6, 2008 |  BC Innovations  |  Markers

mTOR Caveats

In many tumor types, rapamycin is thought to inhibit mammalian target of rapamycin 's regulation of a key transcription factor-hypoxia-inducible factor-1a-that is involved in tumor cell growth and proliferation. A widely used biomarker therefore relies...