BioCentury | Oct 25, 2019
Tools & Techniques

NASH: how non-invasive biomarkers promise to displace biopsies

...use elastography. The ELF test is a composite of three indicators of fibrosis: hyaluronic acid, PIIINP...
...kinase 1 FXR (NR1H4) - Farnesoid X receptor LOXL2 - Lysyl oxidase-like 2 PIIINP - Procollagen III amino terminal peptide...
...Inc. Bristol-Myers Squibb Co. FNIH Acetyl-Coenzyme A carboxylase (ACAC) (ACC) Apoptosis signal-regulating kinase 1 (ASK1) (MAP3K5) Farnesoid X receptor (FXR) (NR1H4) Procollagen III amino terminal peptide (PIIINP) Tissue...
BioCentury | Jun 27, 2019
Distillery Techniques

Patient-derived liver organoids for screening steatohepatitis

...droplet enlargement and hepatocyte ballooning characteristic of the disease. Their supernatants contained elevated levels of procollagen III amino terminal peptide (PIIINP)...
BioCentury | Oct 27, 2017
Clinical News

Gilead reports mixed Phase II data for NASH candidate

...5.5% vs. 12.5%, p=0.1), serum alanine transaminase (ALT) levels (20.5% vs. 6.7%, p=0.176), or serum procollagen III amino terminal peptide (PIIINP)...
...LLC Acetyl-Coenzyme A carboxylase (ACAC) (ACC) Alanine transaminase (ALT) Apoptosis signal-regulating kinase 1 (ASK1) (MAP3K5) Farnesoid X receptor (FXR) (NR1H4) Procollagen III amino terminal peptide (PIIINP) Tissue...
BioCentury | Oct 24, 2017
Clinical News

Gilead reports mixed Phase II data for NASH candidate

...as measured by FibroScan and magnetic resonance elastography, serum alanine transaminase (ALT) levels, or serum procollagen III amino terminal peptide (PIIINP)...
...Inc. Acetyl-Coenzyme A carboxylase (ACAC) (ACC) Alanine transaminase (ALT) Apoptosis signal-regulating kinase 1 (ASK1) (MAP3K5) Farnesoid X receptor (FXR) (NR1H4) Procollagen III amino terminal peptide (PIIINP) Tissue...
BioCentury | Aug 8, 2011
Company News

Siemens sales and marketing update

...therapy response. The test, which has CE Mark approval, uses serum biomarkers hyaluronic acid (HA), procollagen III amino terminal peptide (PIIINP)...
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