BioCentury | Aug 14, 2020
Translation in Brief

Hesperos applies organ-on-a-chip tech to ALS, Sinopharm details interim COVID-19 vaccine readout and more

...prevented the progression of renal fibrosis.TARGETSBRN3A (POU4F1) – POU...
...of Central Florida Cornell University Beijing Biological Products Institute (Sinopharm) POU...
BioCentury | Dec 7, 2018
Tools & Techniques

Germline editing gets technical

...Silver Spring, Md. Targets CCR5 (CD195) - CC chemokine receptor 5 OCT4 (POU5F1; OCT3) - POU...
BioCentury | Jul 12, 2018
Translation in Brief

New Therapeutic Targets and Biomarkers: June 2018

...of Liège Distillery Therapeutics Elongator acetyltransferase complex subunit 3 (ELP3) Small cell lung cancer (SCLC) POU...
BioCentury | Jul 10, 2018
Distillery Therapeutics

Cancer

...disease (thyroid eye disease) and Phase I testing to treat diabetic macular edema (DME). TARGET/MARKER/PATHWAY: POU...
...Spring Harbor Laboratory Insulin-like growth factor (IGF) binding protein 5 (IGFBP5) Insulin-like growth factor-1 (IGF-1) receptor (IGF1R) (CD221) POU...
BioCentury | Jun 27, 2018
Preclinical News

New small cell lung cancer subtype identified

...Laboratory identified a new subtype of small cell lung cancer defined by high levels of POU...
...Spring Harbor Laboratory Insulin-like growth factor (IGF) binding protein 5 (IGFBP5) Insulin-like growth factor-1 (IGF-1) receptor (IGF1R) (CD221) POU...
BioCentury | Jun 13, 2018
Distillery Techniques

Disease models

...The method involves transfecting primary human T cells with a combination of plasmid vectors encoding POU...
...email: wernig@stanford.edu Sandi Wong Stanford University Achaete-scute complex homolog 1 (ASCL1) (MASH1) Myelin transcription factor 1-like (MYT1L) Neurogenin 2 (Ngn2) (Neurog2) POU...
BioCentury | Sep 27, 2017
Translation in Brief

Editing without translation

...at The Francis Crick Institute used CRISPR- Cas9 (CRISPR-associated protein 9) to knock out the POU...
...pathogenic gene mutation in human embryos.” Nature (2017) Lauren Martz, Senior Writer Francis Crick Institute CRISPR-associated protein 9 (Cas9) POU...
BioCentury | Aug 3, 2017
Translation in Brief

New Therapeutic Targets and Biomarkers: July 2017

...targeting SALL2, SRY (sex determining region Y)-box 2 (SOX2), oligodendrocyte transcription factor 2 (OLIG2), and POU...
BioCentury | Jul 25, 2017
Distillery Therapeutics

Cancer

...region Y)-box 2 (SOX2); oligodendrocyte transcription factor 2 (OLIG2); spalt like transcription factor 2 (SALL2); POU...
...CONTACT: Maciej S. Lesniak, Northwestern University, Chicago, Ill. email: maciej.lesniak@northwestern.edu Claire Quang Northwestern University Oligodendrocyte transcription factor 2 (OLIG2) POU...
BioCentury | May 26, 2016
Distillery Techniques

Techniques: Baculovirus-based vector system for transient, simultaneous expression of multiple genes for genome editing or cellular reprogramming

...encoding three neuronal differentiation factors - achaete-scute complex homolog 1 ( ASCL1 ; MASH1 ), POU...
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