BioCentury | May 29, 2020
Distillery Therapeutics

Blocking platelet activation for acetaminophen-induced liver failure

DISEASE CATEGORY: Hepatic INDICATION: Liver failure Inhibiting signaling by the platelet activating receptor CLEC1B could treat acetaminophen-induced liver failure. mRNA levels of PDPN, the cognate ligand of CLEC1B, were higher in tissue from acetaminophen-injured human...
BC Innovations | Mar 29, 2019
Targets & Mechanisms

Next-wave targets at AACR 2019 start filling the blanks in the tumor microenvironment

New and emerging targets at AACR 2019 show cancer researchers are gaining granularity on how to manipulate the tumor microenvironment, a top priority goal for the field. The targets point to emerging strategies for modulating...
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