15:48 , Mar 28, 2018 |  BC Innovations  |  Distillery Techniques

Biomarkers

TECHNOLOGY: SNPs SNPs on nine genomic loci could help predict the risk of osteoarthritis. Genome-wide association studies (GWAS) in 30,727 osteoarthritis patients and 297,191 unaffected subjects identified associations between the disease and SNPs on nine...
07:00 , May 12, 2016 |  BC Innovations  |  Distillery Techniques

Techniques: Plectin (PLEC)-targeting nanoparticle to deliver cancer therapies to pancreatic ductal adenocarcinoma (PDAC) tumors

Drug delivery TECHNOLOGY: Nanoparticles Polymer nanoparticles linked to a PLEC-targeting peptide could be used to deliver therapies to PDAC tumors. The nanoparticles were composed of poly(lactic-co-glycolic acid) (PLGA) polymers, a peptide that bound PLEC ,...
08:00 , Dec 19, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Pancreatic cancer Plectin (PLEC) In vitro and mouse studies suggest inhibiting PLEC could help treat pancreatic cancer. Compared with human pancreatic epithelial cells, human pancreatic...