BioCentury | Mar 5, 2019
Distillery Techniques

Vascularized kidney organoids for modeling renal disease

...housed within a perfusable millifluidic chip to enhance expression of the vascular marker platelet/endothelial cell adhesion molecule 1 (PECAM1; CD31...
BioCentury | Apr 17, 2014
Distillery Therapeutics

Indication: Various

...studies suggest increasing CD31 signaling could help treat inflammatory and autoimmune diseases. In mice, a CD31...
...mouse model of experimental autoimmune encephalomyelitis (EAE), adoptive transfer of dendritic cells treated with a CD31...
BioCentury | Apr 3, 2014
Targets & Mechanisms

Narrowing down graft stenosis

...the neointima using markers specific for endothelia, including platelet/endothelial cell adhesion molecule ( Pecam1 ; Cd31...
BioCentury | Nov 14, 2011
Clinical News

Atu134: Development discontinued

...Molecular target: Platelet/endothelial cell adhesion molecule (PECAM1) (CD31) Description: Short interfering RNA (siRNA) lipoplex targeting CD31...
BioCentury | Oct 21, 2010
Distillery Therapeutics

Indication: Cancer

...Cancer Cancer Platelet/endothelial cell adhesion molecule (PECAM1; CD31) A study in mice suggests that inhibiting PECAM1...
...treat advanced metastatic cancer. In mouse models of late-stage metastatic melanoma or breast cancer, an anti-PECAM1...
...antibody control (p<0.0001). In the same late-stage model of melanoma, a sixth dose of an anti-PECAM1...
BioCentury | Apr 1, 2002
Company News

Massachusetts Institute of Technology other research news

...line using antibodies that target the platelet endothelial cell-adhesion molecule (PECAM-1). The isolated cells expressed CD31...
BioCentury | Mar 18, 2002
Company News

California Pacific Medical Research Institute other research news

Researchers published in the Proceedings of the National Academy of Sciences evidence that CLDCs can be used to deliver protein specific ribozymes to treat cancer. Intravenous treatment with CLDCs encoding an NF-kB specific ribozyme significantly...
BioCentury | Dec 3, 2001
Company News

Pharmacia other research news

...tumors grew more slowly (p<0.01) and had lower vascular density as assessed by staining with anti-CD31...
BioCentury | May 29, 2001
Company News

University of Miami other research news

...University researchers published in Neurology that the plasma of MS patients has more EMPs and CD31...
...progression of MS and may be evidence of blood brain barrier damage. Elevated levels of CD31...
...authors said. University of Miami, Miami, Fla. Product: Endothelial microparticles (EMP) and cellular adhesion molecule CD31...
BioCentury | Dec 6, 1993
Company News

University of Pennsylvania other research news

Researchers at the university's medical center reported on a cell adhesion molecule that is currently in negotiation for licensing with various companies.The platelet-endothelial cell adhesion molecule (PECAM-1) is related to other CAMs and is present...
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