BioCentury | Jan 30, 2020
Distillery Therapeutics

Platelet-derived growth factor isoform as heart attack treatment

...DISEASE CATEGORY: Cardiovascular INDICATION: Myocardial infarction (MI); ischemia/reperfusion injury PDGFAB, an isoform of platelet-derived growth factor...
...mechanically simulated via coronary artery angioplasty balloon occlusion and deflation, systemic infusion of recombinant human PDGFAB...
...contractility and relaxation; and reduced inducible ventricular tachycardia. Next steps include submitting an IND. TARGET/MARKER/PATHWAY: Platelet derived growth factor AB (PDGFAB)...
BioCentury | May 5, 2016
Distillery Techniques

Techniques: Platelet derived growth factor AB (PDGFAB) and Vidaza azacitidine to reprogram terminally differentiated cells into induced multipotent stem cells f

...Drug platforms TECHNOLOGY: Cell therapy Reprogramming terminally differentiated cells with PDGFAB and Vidaza azacitidine could help...
...and Vidaza azacitidine could help generate induced multipotent stem cells for regenerative therapies. Treatment with PDGFAB...
...and fat. In a mouse model of spinal injury, transplants of mouse osteocytes pretreated with PDGFAB...
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