BioCentury | Sep 30, 2020
Deals

As China’s CStone preps for launches, Pfizer buys equity stake and local rights to PD-L1 program

...kinaseIDH1 - Isocitrate dehydrogenase 1PD-1 (PDCD1; CD279) - Programmed cell death 1PDGFRA (PDGFR2; CD140A) - Platelet derived growth factor...
BioCentury | Aug 6, 2020
Product Development

Aug. 5 Quick Takes: Strong quarterly sales of Horizon’s Tepezza, Global Blood’s Oxbryta; plus a setback for DBV and news from Point, Karuna, Evotec-Secarna, Red

...CD221) - Insulin-like growth factor-1 receptor NGF - Nerve growth factor PDGFRA (PDGFR2; CD140A) - Platelet derived growth factor...
...plc Zai Lab Ltd. Deciphera Pharmaceuticals Inc. Secarna Pharmaceuticals GmbH Evotec AG Regeneron Pharmaceuticals Inc. Stem cell factor (SCF) (c-Kit ligand) (KITLG) Platelet derived growth factor...
BioCentury | Jul 14, 2020
Deals

Roche deal clears path for Blueprint’s financial independence

...kinase receptor 2 NRTK3 (TrkC) - Neurotrophic tyrosine kinase receptor 3 PDGFRA (PDGFR2; CD140A) - Platelet derived growth factor...
BioCentury | Jul 7, 2020
Deals

Adding to targeted oncology portfolio, Zai gains China rights to Turning Point’s repotrectinib

...kinase FGFR2b - Fibroblast growth factor (FGF) receptor 2 b isoform PDGFRA (PDGFR2; CD140A) - Platelet derived growth factor...
BioCentury | May 15, 2020
Regulation

Fourth-line GIST showdown ends in an FDA win for Deciphera, a rejection for Blueprint

...c-Kit (KIT; CD117) - Stem cell factor (SCF) receptor tyrosine kinase PDGFRA (PDGFR2; CD140A) - Platelet derived growth factor...
BioCentury | Apr 28, 2020
Product Development

Blueprint stumbles in GIST race, clearing path for Deciphera

...c-Kit (KIT; CD117) - Stem cell factor (SCF) receptor tyrosine kinase PDGFRA (PDGFR2; CD140A) - Platelet derived growth factor...
BioCentury | Mar 17, 2020
Product Development

Phase II data bring Blueprint closer to major market expansion for Ayvakit

...Targets c-Kit (KIT; CD117) - Stem cell factor receptor tyrosine kinase PDGFRA (PDGFR2; CD140A) - Platelet derived growth factor...
BioCentury | Mar 10, 2020
Product Development

March 9 Quick Takes: A first for Boehringer’s Ofev; plus Cel-Sci’s COVID-19 therapy, Sinopharm, AZ, Urovant, Hengrui, Trevena, and Tetra-Shionogi

...Fibroblast growth factor receptor MOR (OPRM1) - Mu opioid receptor PDE-4D - Phosphodiesterase-4D PDGFR - Platelet derived growth factor...
BioCentury | Feb 14, 2020
Product Development

Feb. 13 Product Development Quick Takes: Priority Review for BMS, Seattle Genetics, Deciphera therapies; plus Roche, Ipsen, Merck, Eisai and Amgen-Pfizer

...factor receptor 2 PD-1 (PDCD1; CD279) - Programmed cell death 1 PDGFRA (PDGFR2; CD140A) - Platelet derived growth factor...
BioCentury | Jan 30, 2020
Distillery Therapeutics

Platelet-derived growth factor isoform as heart attack treatment

...contractility and relaxation; and reduced inducible ventricular tachycardia. Next steps include submitting an IND. TARGET/MARKER/PATHWAY: Platelet derived growth factor...
Items per page:
1 - 10 of 643