BioCentury | Dec 2, 2010
Distillery Therapeutics

Indication: Infectious disease

...contact information Infectious disease Influenza virus Platelet activating factor receptor (PTAFR; PAFR) Studies in mice suggest that inhibiting PAFR...
...lung injury and death from influenza A virus infection. In mice infected with H1N1 influenza, Pafr...
...injury and mortality compared with those in infected wild-type controls. In H1N1-infected wild-type mice, a PAFR...
BioCentury | Aug 20, 2009
Targets & Mechanisms

PAF's fever pitch

...the severity of dengue infection in mice, 1 and the group plans to have a platelet activating factor receptor...
...did not show significant efficacy. The logical step was to antagonize the PAF receptor ( PAFR...
...out genetic and pharmacological experiments to test the effects of inhibiting PAFR. Infected mice with Pafr...
BioCentury | Aug 13, 2009
Distillery Therapeutics

Indication: Infectious disease

...in mice suggest that antagonizing PAFR could help prevent severe dengue infection. In dengue-infected mice, PAFR...
...and vascular leakage and delayed lethality compared with dengue-infected wild-type mice. In wild-type mice, a PAFR...
...symptoms of dengue infection and reduced viral load compared with vehicle. Next steps include studying PAFR...
BioCentury | Oct 16, 1995
Company News

Rockefeller University other research news

...spray in the throat to prevent pneumococcus disease, researcher Elaine Tuomanen said. Rockefeller University Product: Platelet activating factor (PAF) receptor...
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