19:55 , Dec 7, 2018 |  BC Extra  |  Preclinical News

UCSD team offers access to newly identified antimalaria leads

A University of California San Diego team has published openly 631 antimalaria compounds identified through a screening campaign, offering the potential building blocks of a chemical vaccine that targets malaria in the early stages of...
01:14 , Oct 6, 2018 |  BioCentury  |  Finance

Large cap comeback

The biotech sector continued to be a stock pickers’ market through 3Q18 as there was a near even split between global biotech stocks that gained and lost value in the quarter. While 1H18 saw investors...
22:07 , Sep 13, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: August 2018

New Therapeutic Targets and Biomarkers: August 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database in August 2018. Therapeutic targets are defined as any protein, gene or other...
17:50 , Aug 29, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Malaria In vitro , cell culture and mouse studies identified asparagine ethylenediamine-based inhibitors of Plasmodium falciparum proteasome subunit β type 5 that could help treat malarial infection. Screening of a library of tool compound...
15:53 , Aug 23, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Malaria Cell culture and mouse studies identified an inhibitor of P. falciparum proteasome subunit β type 2 and proteasome subunit β type 5 that could help treat malaria. Chemical synthesis and testing of vinyl...
23:05 , Aug 1, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: July 2018

New Therapeutic Targets and Biomarkers: July 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during July 2018. Therapeutic targets are defined as any protein, gene or other...
17:18 , Jul 27, 2018 |  BC Week In Review  |  Clinical News

FDA committee: 60 Degrees' malaria candidate safe and effective

FDA's Antimicrobial Drugs Advisory Committee voted that malaria candidate Arakoda tafenoquine (60P003) from 60 Degrees Pharmaceuticals LLC (Washington, D.C.) is effective and safe. The panel voted 11-2 that tafenoquine was effective in preventing malaria infection...
15:27 , Jul 27, 2018 |  BC Week In Review  |  Clinical News

FDA approves GSK's Krintafel to prevent malaria relapse

GlaxoSmithKline plc (LSE:GSK; NYSE:GSK) and Medicines for Malaria Venture (MMV) said FDA approved single-dose Krintafel tafenoquine to prevent relapse of Plasmodium vivax malaria in patients ages 16 and older who are receiving antimalarial therapy for...
20:59 , Jul 26, 2018 |  BC Extra  |  Company News

FDA committee: 60 Degrees' malaria candidate safe and effective

FDA's Antimicrobial Drugs Advisory Committee voted that malaria candidate tafenoquine (60P003) from 60 Degrees Pharmaceuticals LLC (Washington, D.C.) is effective and safe. The panel voted 11-2 that tafenoquine was effective in preventing malaria infection in...
19:05 , Jul 24, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Malaria Mouse studies suggest an RNA-based vaccine encoding Plasmodium MIF could help prevent malaria infection. The vaccine consists of a lipid nanoparticle (LNP) loaded with Plasmodium MIF encoded by an alphaviral RNA replicon. In...