23:22 , Feb 20, 2019 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Malaria Cell culture, patient sample and mouse studies identified a bitriazine-based compound that could help treat malaria. Chemical synthesis and testing of bitriazine analogs in human erythrocyte-based assays of Plasmodium falciparum growth identified a...
21:37 , Feb 14, 2019 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: January 2019

New Therapeutic Targets and Biomarkers: January 2019 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during January. Therapeutic targets are defined as any protein, gene or other molecule...
00:06 , Jan 23, 2019 |  BC Innovations  |  Distillery Techniques

Assays and screens

TECHNOLOGY: Diagnostic assays An assay for detecting P. falciparum PSSP17 in saliva could help rapidly diagnose clinical and subclinical P. falciparum infection at the point of care. The assay comprises mixing saliva samples with two...
22:04 , Jan 8, 2019 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Malaria In vitro and cell culture studies identified two P. falciparum PK9 inhibitors that could help treat malaria. Screening of a kinase inhibitor library in HEK cells expressing P. falciparum PK9, in vitro binding...
02:49 , Jan 5, 2019 |  BioCentury  |  Finance

Ready to launch

  The proposed $74 billion takeout of Celgene Corp. by Bristol-Myers Squibb Co. will not shift buysider attention away from upcoming and maturing drug launches heading into 2019, with plenty to track following a record...
19:55 , Dec 7, 2018 |  BC Extra  |  Preclinical News

UCSD team offers access to newly identified antimalaria leads

A University of California San Diego team has published openly 631 antimalaria compounds identified through a screening campaign, offering the potential building blocks of a chemical vaccine that targets malaria in the early stages of...
01:14 , Oct 6, 2018 |  BioCentury  |  Finance

Large cap comeback

The biotech sector continued to be a stock pickers’ market through 3Q18 as there was a near even split between global biotech stocks that gained and lost value in the quarter. While 1H18 saw investors...
22:07 , Sep 13, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: August 2018

New Therapeutic Targets and Biomarkers: August 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database in August 2018. Therapeutic targets are defined as any protein, gene or other...
17:50 , Aug 29, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Malaria In vitro , cell culture and mouse studies identified asparagine ethylenediamine-based inhibitors of Plasmodium falciparum proteasome subunit β type 5 that could help treat malarial infection. Screening of a library of tool compound...
15:53 , Aug 23, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Malaria Cell culture and mouse studies identified an inhibitor of P. falciparum proteasome subunit β type 2 and proteasome subunit β type 5 that could help treat malaria. Chemical synthesis and testing of vinyl...