BC Innovations | Mar 13, 2019
Distillery Therapeutics

Inhibiting PIEZO1 for nerve damage

DISEASE CATEGORY: Neurology INDICATION: Nerve damage Fruit fly and mouse studies suggest inhibiting PIEZO1 could help treat nerve damage. In two Drosophila models of sensory nerve injury and one Drosophila model of motor nerve injury,...
BC Innovations | Dec 11, 2014
Targets & Mechanisms

PIEZO de resistance

A pair of recently identified calcium channels- PIEZO1 and PIEZO2-control the response of cartilage to heavy loads and offer new targets for joint injury and osteoarthritis, according to findings from a team at Duke University...
BC Innovations | Dec 11, 2014
Distillery Therapeutics

Indication: Musculoskeletal disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Cartilage repair Piezo-type mechanosensitive ion channel component 1 (PIEZO1); PIEZO2 Cell and tissue culture studies suggest inhibiting PIEZO1 and PIEZO2 could prevent load-induced articular...
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