BioCentury | Sep 16, 2020
Product Development

Pace of Monjuvi’s growth may dictate how quickly MorphoSys can rebuild its pipeline

...I/II M-PLACE trial of felzartamab to treat anti-PLA2R1-positive...
...said.TARGETSGM-CSF (CSF2) – Granulocyte macrophage colony-stimulating factorPLA2R1 (PLA2R...
BioCentury | Apr 11, 2020
Management Tracks

Harpal Kumar named president of Grail Europe; plus Notable, Oncoceutics, ReAlta, Parker Institute

Grail Inc. hired Sir Harpal Kumar as president of the liquid biopsy company’s Europe operations. He was SVP and head of innovation in Europe, the Middle East and Africa at Johnson & Johnson (NYSE:JNJ) and...
BioCentury | Jun 1, 2019
Product Development

ASCO 2019 abstracts show solid tumor race heating up among bispecifics and CAR Ts

While strong progress in CAR T therapies will again feature at this year’s ASCO meeting, bispecific antibodies are having a moment -- making more inroads into solid tumors than CAR Ts and branching out via...
BioCentury | Aug 29, 2018
Distillery Techniques

Imaging; other

TECHNOLOGY: MRI; computational models A computational model based on functional MRI and clinical presentation could predict whether unconscious brain injury patients will recover consciousness within 12 months. The model incorporates functional MRI imaging, injury etiology,...
BioCentury | Nov 14, 2017
Distillery Techniques

Assays and screens; biomarkers

TECHNOLOGY: Diagnostic assays; tissue markers Profiling a subset of gut microbiota could help diagnose atherosclerotic cardiovascular disease. Metagenomic analysis of fecal samples from 218 patients with stable angina, unstable angina or MI, and 187 healthy...
BioCentury | Oct 24, 2017
Distillery Techniques

Disease models

TECHNOLOGY: Cell models A biobank of insertional mutagenesis-derived haploid mouse ESCs could be used to link genes to disease-related phenotypes in homogeneous cell populations. The biobank consists of over 100,000 haploid mouse ESCs with genetically...
BioCentury | Sep 28, 2017
Preclinical News

Researchers report first Haplobank data

In a paper published in Nature , researchers at the Austrian Academy of Sciences and colleagues reported the first data from Haplobank, an open-access haploid mouse embryonic stem cell (ESC) bank created in collaboration with the...
BioCentury | Jan 18, 2017
Distillery Therapeutics

Infectious disease

INDICATION: Viral infection Cell culture and mouse studies suggest inhibiting PLA2G16 could help treat picornaviral infections. In HeLa cells infected with coxsackievirus, enterovirus, human rhinovirus or other picornaviruses, PLA2G16 knockout decreased infectivity by picornaviruses compared...
BioCentury | Nov 18, 2016
Clinical News

A-101: Ph III SEBK-301 and SEBK-302 data

Top-line data from the identical, double-blind, U.S. Phase III SEBK-301 and SEBK-302 trials in a total of 937 patients with 4 target lesions on the face, trunk and extremities showed that up to 2 applications...
BioCentury | Mar 31, 2016
Translation in Brief

Slow and steady

AstraZeneca plc (LSE:AZN; NYSE:AZN) and Bind Therapeutics Inc. (NASDAQ:BIND) have joined forces to stretch the therapeutic index of a kinase inhibitor that had stumbled in the clinic. The partners developed a nanoparticle formulation that slowed...
Items per page:
1 - 10 of 354