23:38 , Oct 24, 2017 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: Cell models A biobank of insertional mutagenesis-derived haploid mouse ESCs could be used to link genes to disease-related phenotypes in homogeneous cell populations. The biobank consists of over 100,000 haploid mouse ESCs with genetically...
03:49 , Sep 28, 2017 |  BC Extra  |  Preclinical News

Researchers report first Haplobank data

In a paper published in...
20:40 , Jan 18, 2017 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Viral infection Cell culture and mouse studies suggest inhibiting PLA2G16 could help treat picornaviral infections. In HeLa cells infected with coxsackievirus, enterovirus, human rhinovirus or other picornaviruses, PLA2G16 knockout decreased infectivity by picornaviruses compared...
08:00 , Jan 22, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Endocrine disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine disease Obesity Phospholipase A2, group XVI (PLA2G16; AdPLA) Studies in mice suggest that ablation of AdPLA, which is highly expressed only...