BioCentury | Oct 24, 2017
Distillery Techniques

Disease models

...biobank in a HEK cell-based assay of response to rhinoviral infection identified a mutation in phospholipase A2 group XVI (PLA2G16)...
...43kDa (GJA1) (CX43) (connexin-43) Hemopoietic cell kinase (HCK) MDS1 and EVI1 complex locus (MECOM) Phosphodiesterase-I beta (ENPP3) (NPP3) (CD203c) Phospholipase A2 group XVI (PLA2G16) Phospholipase...
BioCentury | Sep 28, 2017
Preclinical News

Researchers report first Haplobank data

...group performed a genome-wide forward screen of Haplobank cells for resistance to rhinovirus and identified phospholipase A2 group XVI (PLA2G16)...
...immune response to rhinovirus infection. In human embryonic kidney (HEK) cells infected with rhinovirus, inactivating PLA2G16...
...to discover and develop small molecules against PLA2G16 to treat viral infections. The partners have PLA2G16...
BioCentury | Jan 18, 2017
Distillery Therapeutics

Infectious disease

...INDICATION: Viral infection Cell culture and mouse studies suggest inhibiting PLA2G16 could help treat picornaviral infections...
...increased survival. Next steps by Haplogen GmbH and Evotec AG include developing PLA2G16 inhibitors. TARGET/MARKER/PATHWAY: Phospholipase A2 group XVI (PLA2G16)...
...2017 doi:10.1038/nature21032 CONTACT: Thijn Brummelkamp, Netherlands Cancer Institute, Amsterdam, the Netherlands email: t.brummelkamp@nki.nl Winnie Pong Netherlands Cancer Institute Phospholipase A2 group XVI (PLA2G16) Viral...
BioCentury | Jan 22, 2009
Distillery Therapeutics

Indication: Endocrine disease

...Target/marker/pathway Summary Licensing status Publication and contact information Endocrine disease Obesity Phospholipase A2, group XVI (PLA2G16...
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