BioCentury | Nov 10, 2020
Regulation

Label expansions coming at a rapid clip for Foundation’s blood-based companion cancer diagnostic

...cancer 1 early onset (BRCA1) Breast cancer 2 early onset (BRCA2) Ataxia telangiectasia mutated (ATM) Anaplastic lymphoma kinase (ALK) Phosphoinositide 3-kinase catalytic subunit alpha polypeptide (PIK3CA) (p110alpha) Cancer Prostate...
BioCentury | Aug 8, 2020
Translation in Brief

Cocrystal’s COVID-19 antivirals; plus a portable breast cancer diagnostic, Tarveda mini-drug conjugate for solid tumors, and more

...protease (SARS-CoV-2 3CLpro) (SARS-CoV-2 NSP5) (SARS-CoV-2 Mpro) (SARS-CoV-2 main protease) Heat shock protein 90 (Hsp90) Phosphoinositide 3-kinase (PI3K) Phosphoinositide 3-kinase catalytic subunit alpha polypeptide (PIK3CA) (p110alpha) Epidermal...
BioCentury | Nov 8, 2019
Preclinical News

Nov. 7 Preclinical Quick Takes: NIH drafts policy requiring more data sharing; plus Unum, Mission-BioLegend, DCprime and more

...1 BioCentury Staff NIH Unum Therapeutics Inc. Seattle Genetics Inc. Mission Bio Inc. Phosphoinositide 3-kinase (PI3K) Programmed cell death 1 (PD-1) (PDCD1) (CD279) Phosphoinositide 3-kinase catalytic subunit alpha polypeptide (PIK3CA) (p110alpha)...
BioCentury | Sep 12, 2019
Distillery Therapeutics

Inhibition of G9A and DNMT methyltransferases in bladder cancer

...Paramio, CIEMAT, Madrid, Spain e-mail: jesusm.paramio@ciemat.es Inhua Muijrers-Chen Euchromatic histone-lysine N-methyltransferase 2 (EHMT2) (G9A) DNA methyltransferase DNA (cytosine-5-)-methyltransferase 1 (DNMT1) Phosphoinositide 3-kinase catalytic subunit alpha polypeptide (PIK3CA) (p110alpha) Programmed...
BioCentury | Aug 15, 2019
Distillery Techniques

Mutation combination as endometrial cancer biomarker

...Health System, Grand Rapids, Mich. e-mail: rlc@msu.edu Sandi Wong Michigan State University Van Andel Institute AT-rich interaction domain 1A (ARID1A) Phosphoinositide 3-kinase catalytic subunit alpha polypeptide (PIK3CA) (p110alpha) Endometrial...
BioCentury | Aug 9, 2019
Preclinical News

Aug. 8 Preclinical Quick Takes: Mayo Clinic assay for residual disease; plus camouflage for bacterial agents, Elicio's KRAS vaccine and more

...Inc. Van Andel Institute Agglutinin-like sequence 3 (ALS3) AT-rich interaction domain 1A (ARID1A) CC chemokine receptor 5 (CCR5) (CD195) K-Ras (KRAS) Phosphoinositide 3-kinase catalytic subunit alpha polypeptide (PIK3CA) (p110alpha) Candida Endometrial...
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