BC Extra | Nov 8, 2019
Preclinical News

Nov. 7 Preclinical Quick Takes: NIH drafts policy requiring more data sharing; plus Unum, Mission-BioLegend, DCprime and more

NIH pitches policy for greater sharing of data  NIH has published a draft of the NIH Policy for Data Management and Sharing to promote wider sharing of data and results generated from NIH-funded grant work...
BC Innovations | Sep 12, 2019
Distillery Therapeutics

Inhibition of G9A and DNMT methyltransferases in bladder cancer

DISEASE CATEGORY: Cancer INDICATION: Bladder cancer Dual inhibition of G9A and DNMT methyltransferases, in combination with cisplatin and anti-programmed cell death 1 ligand 1 (PD-L1), could help to treat bladder cancer. A tool compound that...
BC Innovations | Aug 15, 2019
Distillery Techniques

Mutation combination as endometrial cancer biomarker

TECHNIQUES CATEGORY: Biomarkers TECHNOLOGY: Gene profiling; tissue markers; SNPs Michigan State University and Van Andel Institute researchers have linked a combination of two mutations -- a loss-of-function mutation in tumor suppressor ARID1A plus an activating...
BC Extra | Aug 9, 2019
Preclinical News

Aug. 8 Preclinical Quick Takes: Mayo Clinic assay for residual disease; plus camouflage for bacterial agents, Elicio's KRAS vaccine and more

Mayo Clinic liquid biopsy identifies breast cancer residual disease  A Mayo Clinic team reported in a Science Translational Medicine article that a personalized multiplex sequencing approach called TARDIS (targeted digital sequencing) could accurately distinguish pathological...
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