BioCentury | Sep 22, 2016
Distillery Therapeutics
Therapeutics: Phosphoinositide 3-kinase class 2 subunit β polypeptide (PI3KC2B); myotubularin 1 (MTM1); phosphatidylinositol-3-phosphate (PI3P)
...Musculoskeletal disease INDICATION: Musculoskeletal Mouse and zebrafish studies suggest inhibiting PI3KC2B could help treat myotubular myopathy...
...by mutations in MTM1 . In a mouse model of the disease, muscle-specific knockout of PI3KC2B...
...normal PI3KC2B expression or vehicle. In a zebrafish model of myotubular myopathy, three inhibitors of PI3KC2B...
...by mutations in MTM1 . In a mouse model of the disease, muscle-specific knockout of PI3KC2B...
...normal PI3KC2B expression or vehicle. In a zebrafish model of myotubular myopathy, three inhibitors of PI3KC2B...
