07:00 , May 14, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Phosphatidylinositol 4-kinase catalytic β (PI4KB; PI4KIIIβ)

Infectious disease INDICATION: Viral infection In vitro studies suggest inhibitors of PI4KB could help treat RNA virus infections. Chemical synthesis and in vitro testing of pyrazolopyrimidine analogs identified multiple compounds that selectively inhibited PI4KB with IC50 values...