BioCentury | Jan 31, 2018
Distillery Therapeutics

Cancer

INDICATION: Brain cancer; breast cancer; colorectal cancer Cell culture and mouse studies identified an indole-quinoline-based dual PIP4K2A/PIP4K2C inhibitor that could help treat Ras-driven glioma, breast cancer and colorectal cancer. Screening of a small molecule library...
BioCentury | Jan 17, 2018
Distillery Therapeutics

Neurology

INDICATION: Huntington's disease (HD) Patient sample, mouse and fruit fly studies suggest inhibiting PIP4K2C could help treat HD. In two fibroblast cell lines derived from HD patients and neurons from a mouse model of HD,...
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