07:00 , Sep 22, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Phosphoinositide 3-kinase class 2 subunit β polypeptide (PI3KC2B); myotubularin 1 (MTM1); phosphatidylinositol-3-phosphate (PI3P)

Musculoskeletal disease INDICATION: Musculoskeletal Mouse and zebrafish studies suggest inhibiting PI3KC2B could help treat myotubular myopathy, which is caused by mutations in MTM1 . In a mouse model of the disease, muscle-specific knockout of PI3KC2B...
07:00 , Aug 5, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Fungal Infection Phosphatidylinositol-3-phosphate (PI3P) In vitro and cell culture studies suggest that blocking the cell surface phospholipid PI3P could help treat fungal infections. In...