BioCentury | Aug 23, 2012
Distillery Therapeutics

Indication: Endocrine/metabolic disease

...inhibiting PexRAP could help treat diabetes and obesity. In mouse adipocytes, small hairpin RNA against PexRAP...
...PPARg target genes compared with scrambled shRNA. In mice fed a high-fat diet, shRNA against PexRAP...
...compared with scrambled shRNA and improved glucose tolerance. Next steps include defining the biology of PexRAP...
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