BioCentury | Mar 31, 2016
Distillery Techniques

DISEASE MODELS

...knockouts PTCHD1-knockout mice could be useful for screening therapies to help treat ADHD. Mice with PTCHD1...
...thalamic reticular nucleus recapitulated attention deficits and hyperactive behaviors seen in ADHD patients. In the PTCHD1-knockout...
...and testing compounds that target the thalamic reticular nucleus in animal models of ADHD. DESCRIPTION: Patched domain containing 1 (PTCHD1)-knockout...
BioCentury | Dec 14, 2015
Product Development

Following CoMMpass

Amidst a flood of promising data for hot targets, indications and technologies at this year's American Society of Hematology meeting, one collection of presentations stands out not only for the wide-reaching implications of their data,...
BioCentury | Oct 14, 2010
Distillery Therapeutics

Indication: Neurology

...suggest that mutations in PTCHD1 could be associated with autism spectrum disorders and intellectual disability. PTCHD1...
...disorders and three with related intellectual disabilities, missense mutations in or near the X-chromosome gene PTCHD1...
...than 500 controls without autism. Next steps could include exploring the therapeutic potential of targeting PTCHD1...
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