22:36 , Sep 6, 2018 |  BC Extra  |  Preclinical News

Salk team reports gene therapy can re-grow skin in cutaneous ulcers

Researchers from Salk Institute for Biological Studies and colleagues developed a gene therapy delivering four transcription factors to regenerate epithelial cells from wound-resident mesenchymal cells in cutaneous ulcers. By delivering reprogramming factors directly to a...
18:33 , Aug 29, 2018 |  BC Innovations  |  Translation in Brief

Accelerated healing

In a Science Translational Medicine paper published last month, an NIH team showed SRY (sex determining region Y)-box 2 (SOX2) and paired-like homeodomain 1 (PITX1) can activate wound healing, and is now evaluating the transcription...
08:00 , Jan 7, 2016 |  BC Innovations  |  Distillery Techniques

Techniques: Five-gene CpG methylation signature to predict outcomes in clear cell renal cell carcinoma (ccRCC) patients

Biomarkers EH domain binding protein 1-like 1 (EHBP1L1) forkhead box E3 (FOXE3) paired-like homeodomain 1 (PITX1) Ras and RAB interactor 1 (RIN1) twinfilin actin binding protein 2 (TWF2) Sun Yat-sen University...