BioCentury | Jun 11, 2015
Distillery Therapeutics

Therapeutics: P. falciparum prolyl-tRNA synthetase (PfPRS)

...and testing in yeast-based culture systems identified halofuginol, febrifugine and other analogs as inhibitors of PfPRS...
...observed for halofuginone. Next steps could include drug metabolism and pharmacokinetic studies on halofuginol. TARGET/MARKER/PATHWAY: P. falciparum prolyl-tRNA synthetase (PfPRS)...
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