08:00 , Jan 7, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: P. falciparum plasmepsin I; P. falciparum plasmepsin II; P. falciparum plasmepsin IV

Infectious disease INDICATION: Malaria Cell culture studies identified aminoquinazolinone-based inhibitors of Plasmodium falciparum plasmepsins I, II and IV that could help treat malaria. Chemical synthesis and in vitro testing of aminoquinazolinone analogs yielded multiple compounds...